13 May 2002:  An update from Ethan's Mom to her co-workers at Veridian

Hi, everyone ~

I just wanted to say thank you for all of your kind words of encouragement.  Many of you have dropped me short notes to offer support and to let me know that we're in your thoughts.  I've even gotten notes from people I've never met.  Even though I haven't been able to respond, please know that I do appreciate your thoughtful words and have found each and every note very moving.  Its been helpful for me to remember that there's a whole different world out there, besides the one we've been living in for the last week.

As you might imagine, Albert and I have quickly become brain experts.  My 10th grade biology teacher was not very compassionate with me over the whole frog-dissecting incident, but I think he'd be proud of me now.  In just one (very long) week, I can converse with the best of them.  Here's a little information about what we're up against...

Pediatric brain tumors are sometimes very difficult to diagnose and to treat, but surprisingly are the 2nd most common form of cancer in children - second only to leukemia.   Ethan's tumor was located in the right occipital lobe, which controls vision and some cognitive reasoning.  The tumor itself and the surgical removal have almost certainly caused a neural deficit, but the extent of the deficit may not ever be fully understood - and certainly not even estimated until he is much older and can be thoroughly tested.   He's very likely to have some difficulty reading when he is older, as he may not be completely able to translate the input he receives from his eyes.

Pediatric brain tumors are full of irregularities.  It is very challenging for the Pathologists to determine which irregularities are normal and attributable to age (young brains still developing) and which are abnormal in the sense that they are actively destroying healthy brain tissue.  During our final consultation with the Neuroradiologist, Neurosurgeons and Oncologist on Friday, I counted at least 8 different Pathologists who were all consulting on the diagnosis... most of whom were Pediatric Neuropathologists (who knew there were such specialties??).  There is also a team at the Johns Hopkins Oncology Center doing an secondary independent Pathological assessment.   We hope for a final report by the end of this week which will help define the course of further treatment. 

As I told Neal, the preliminary pathology report suggested that the tumor was indeed malignant, or fast-growing.  In the world of brain tumors, benign and malignant are almost misnomers.  Tumors are designated as slow-growing (where benign terminology is sometimes used) and fast-growing (referred to as malignant).  Regardless of their classification, nearly every brain tumor needs to be removed if it is surgically accessible.  Further, because the Pathology of these is so complex, many pediatric brain tumors (benign or malignant) receive similar treatment protocols (chemotherapy and/or radiation) because few, if any, tumors are allowed to simply exist.  There's just too much at stake in the brain.  Even a slow-growing or benign tumor can be life-threatening if left untreated.

The World Health Organization uses a 4-grade classification system for brain tumors, with each grade specifying an increased degree of malignancy.

Grade I - Very slow growing with excellent prognosis for long-term survival.
Grade II - Relatively slow growing, can reoccur and sometimes reoccur as higher grade
Grade III - Fast growing and tend to reoccur
Grade IV - Reproduce rapidly are likely to reoccur.

The grading system is not entirely precise and therefore open to the subjective assessment of the Pathologist(s).  The benign/malignant distinction is between grades II and III, which is also where the most gray area exists.  Its also not uncommon for one tumor to contain several grades of cells.  The highest grade cell within the tumor determines the final classification.  Even if the vast majority of the tumor is grade I, a single grade III cell will tip it into the malignant category.

Our neurosurgeon called last night to give us some good news, which is that the results of his spinal tap came in and that all of his fluid is clear... nothing has spread into the rest of his central nervous system.  For us, we interpret this in one of two ways:   Either the tumor is slow-growing or if its fast-growing, we may have caught it very early.  Final Pathology is due late this week or early next, and its possible that the grading may be different from that suspected in the preliminary assessment.

Ethan is doing pretty well.  Yesterday was a very hard day for him... his medications made him very sick.  Today seems much better so far.  Both he and Kyra are experiencing very odd sleep patterns, so of course Albert & I are too.  Just one more interesting aspect to our life right now. 

We have a follow-up appointment with his neurosurgeon on Friday and hope to have more information about the state of his recovery.  We also hope to get a lot of insurance questions answered.  A cheerful voice called us this morning to tell us that the neurosurgeon is out-of-network.  Uuugh! Brain surgeons are probably not too expensive, right?!?!?  

I wish there were courses offered in navigating health insurance...  I just came to closure on a 7-month insurance snafu in which the anesthesiologist erroneously billed my epidural (which, by the way, was too-little-too-late this time around...) to "baby-girl-Gumabay".  Since baby girls have little need for epidurals, the insurance company would not pay the claim.  AND, on an entirely different level, this service was rendered just minutes prior to 'baby-girl-Gumabay's" arrival, but technically the day before Kyra's birth date, causing an indescribable insurance headache to ensue.  But I digress...  I'm optimistic that we'll be able to straighten out the impending insurance game before Ethan goes to college.

Thank you again for your support...  I hope none of you ever have to experience this type of thing first hand to fully understand how much your support has meant to me and to my family.

Warmest Regards,

Kim (Bert, Ethan, and little Kyra)

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